Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system

The purpose of the present investigation was to prepare matrix tablets of naproxen using a hydrophobic polymer, i.e., Eudragit RLPO, RSPO, and combination of both, by wet granulation method.The tablets were further coated with different concentrations of Touch And Feel Book Eudragit S-100, a pH-sensitive polymer, by dip immerse method.In vitro drug

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Systematic Evaluation of Whole-Genome Sequencing Based Prediction of Antimicrobial Resistance in Campylobacter jejuni and C. coli

The increasing prevalence of antimicrobial resistance (AMR) in Campylobacter spp.is a global concern.This study evaluated the use of whole-genome sequencing (WGS) to predict AMR in Campylobacter jejuni and C.coli.A panel of 271 isolates recovered from Canadian poultry was used to compare AMR genotype to antimicrobial susceptibility testing (AST) re

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Anesthetic management of a morbidly obese patient with endometrial cancer during robot-assisted laparoscopic surgery

Abstract Background The number of robot-assisted surgeries being performed has increased in recent ULTRA-SLEEK CONDITIONER years, even in patients with risk factors, such as obesity, owing to advancements in medical technologies.We here report the anesthetic management of a morbidly obese woman who underwent robot-assisted surgery.Case presentation

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Multi-bioinformatics revealed potential biomarkers and repurposed drugs for gastric adenocarcinoma-related gastric intestinal metaplasia

Abstract Biomarkers associated with the progression from gastric intestinal metaplasia (GIM) to gastric adenocarcinoma (GA), i.e., GA-related GIM, could provide valuable insights into identifying patients with increased risk for GA.The aim of this study was to utilize multi-bioinformatics to reveal potential biomarkers for the GA-related GIM and pr

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